BK virus encephalitis without concurrent hemorrhagic cystitis in an allogeneic hematopoietic stem cell transplant recipient
نویسندگان
چکیده
TO THE EDITOR: The BK virus (BKV) is a human polyomavirus of the Papovaviridae family and causes clinical disease mainly in immunocompromised hosts such as patients infected with human immunodeficiency virus or transplant recipients [1]. Only a few cases of BKV encephalitis have been reported in hematopoietic stem cell (HSC) transplant recipients, with the majority of cases presenting with concurrent hemorrhagic cystitis [2-4]. In this paper, we report a patient with BKV encephalitis without concurrent hemorrhagic cystitis who received allogeneic stem cell transplantation from a matched sibling donor for treatment of a second relapse of diffuse large B cell lymphoma following autologous HSC transplantation (HSCT).
منابع مشابه
Hemorrhagic Cystitis in a Liver Transplant Recipient Secondary to BK Virus
The association between BK virus infection and hemorrhagic cystitis (HC) in hematopoietic stem cell transplant (HSCT) recipients is well established. However, BK virus-associated HC has not been described in liver transplant (LT) recipients. We present a case of BK virus-associated HC in a LT recipient. Our patient presented with worsening liver function tests 2 years after transplantation and ...
متن کاملBK Polyomavirus Hemorrhagic Cystitis following Allogeneic Bone Marrow Transplant with Haploidentical Related Donor: Case Reports from Two Patients
Hemorrhagic cystitis is a common complication in allogeneic bone marrow transplant recipients [1]. The association of BK virus cystitis and allogeneic bone marrow transplant was first described two decades ago [2]. The incidence of hemorrhagic cystitis in allogeneic bone marrow transplant patients is reported up to 70%, while BK viruria after allogeneic bone marrow transplant is detected in 50 ...
متن کاملBK Virus-associated Hemorrhagic Cystitis in Patients with Allogeneic Hematopoietic Cell Transplantation: Report of Three Cases
BK viras is a human polyoma viras. It is acquired in early childhood and remains life-long latent in the genitourinary system. BK virus replication is more common in receiving immunosuppressive therapy receiving patients and transplant patients. BK virus could cause hemorrhagic cystitis in patients with allogeneic stem cell transplantation. Hemorrhagic cystitis is a serious complication of hema...
متن کاملBK viremia precedes hemorrhagic cystitis in children undergoing allogeneic hematopoietic stem cell transplantation.
BK virus is associated with hemorrhagic cystitis after hematopoietic stem cell transplantation (HSCT), although evidence supporting a causal relationship remains limited. Although BK viruria is common after HSCT, BK viremia may better predict clinically significant cystitis, similar to its predictive value for nephropathy after kidney transplantation. We hypothesized that BK viremia would prece...
متن کاملHemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection, preparative regimen intensity and donor type.
BACKGROUND Hemorrhagic cystitis is a common cause of morbidity after allogeneic stem cell transplantation, frequently associated with BK virus infection. We hypothesized that patients with positive BK viruria before unrelated or mismatched related donor allogeneic hematopoietic stem cell transplantation have a higher incidence of hemorrhagic cystitis. DESIGN AND METHODS To test this hypothesi...
متن کامل